1

Oxygenation via C-H/C-C Bond Activation with Molecular Oxygen

ACCOUNTS OF CHEMICAL RESEARCH

Yu-Feng Liang, Ning Jiao

20.268

2

Combination antitumor therapy with targeted dual-nanomedicines.

Advanced Drug Delivery Reviews

Wenbing Dai, Xiaoyou Wang, Ge Song, Tongzhou Liu, Bing Hea, Hua Zhang , Xueqing Wang, Qiang Zhang

17.645

3

Identifying GAPDH as a Novel Cyclic Adenosine Diphosphoribose (cADPR) Binding Protein byPhotoaffinity Protein-Ligand Labeling Approach

Journal of the American Chemical Society

Kehui Zhang, Wei Sun, Lihong Huang, Kaiyuan Zhu, Longchao Zhu, Qian Wang,Yingying Lu, Hongmin Zhang, HongweiJin, Li-He Zhang*, Liangren Zhang*, Jianbo Yue*

13.858

4

CDYL suppresses epileptogenesis through repression of axonal Nav1.6 sodium channel expression

Nature Communications

Liu YQ, Lai SR, Ma WN, Ke W, Zhang C, Liu SM, Zhang Y, Pei F, Li SY, Yi M, Shu YS, Shang YF, Liang J, and Huang Z

12.210

5

Total synthesis of mycobacterial arabinogalactan containing 92 monosaccharide units

Nature Communications

Yong Wu, Decai Xiong, Sicong Chen, Yongshi Wang, Xinshan Ye

12.124

6

Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes

Angew. Chem. Int. Ed.

Song Song, Yiqun Zhang, Adeli Yeerlan, Bencong Zhu, Jianzhong Liu, Ning Jiao

11.994

7

Oxygenation of Simple Olefins through Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes

Angew. Chem. Int. Ed.

Jianzhong Liu+, Xiaojin Wen+, Chong Qin+, Xinyao Li, Xiao Luo, Ao Sun, Bencong Zhu,
Song Song,* Ning Jiao*

11.994

8

Selective -Oxyamination and Hydroxylation of Aliphatic Amides

Angew. Chem. Int. Ed.

Xinwei Li, Fengguirong Lin, Kaimeng Huang, Jialiang Wei, Xinyao Li, Xiaoyang Wang,
Xiaoyu Geng, and Ning Jiao*

11.994

9

Anisotropy in Shape and Ligand-Conjugation of Hybrid Nanoparticulates Manipulates the Mode of Bio–Nano Interaction and Its Outcome.

Advanced Functional Materials

Xiaoyou Wang, Li Lin, Renfa Liu, Min Chen, Binlong Chen, Bo He, Bing He, Xiaolong Liang, Wenbing Dai, Hua Zhang, Xueqing Wang, Yiguang Wang, Zhifei Dai,* Qiang Zhang*

11.774

10

Dual-functional drug liposomes in treatment of resistant cancers.

Adv Drug Deliv Rev

Mu LM, Ju RJ, Liu R, Bu YZ, Zhang JY, Li XQ, Zeng F, Lu WL

11.764

11

Ergot alkaloids: synthetic approaches to lysergic acid and clavine alkaloids

Nat. Prod. Rep.

Haichao Liu, Yanxing Jia

11.014

12

Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy

PNAS, Proceedings of the National Academy of Sciences OF The United States of America

Li-Xi Liao, Xiao-Min Song, Li-Chao Wang, Hai-Ning Lv, Jin-Feng Chen, Dan Liu, Ge Fu, Ming-Bo Zhao, Yong Jiang, Ke-Wu Zeng, Peng-Fei Tu

9.661

13

A Nanosystem of Amphiphilic Oligopeptide-Drug Conjugate Actualizing Both αvβ3 Targeting and Reduction-Triggered Release for Maytansinoid.

Theranostics

Yanqin Liang*, Suxin Li*, Xiaoyou Wang, Bo He, Bing He, Wenbing Dai, Hua Zhang, Xueqing Wang, Yiguang Wang, Demin Zhou, Qiang Zhang

9.222

14

Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment

Theranostics

Binlong Chen, Wenbing Dai, Bing He, Hua Zhang, Xueqing Wang, Yiguang Wang, Qiang Zhang*

9.222

15

Caged circular siRNAs for photomodulation of gene expression in cells and mice

Chem. Sci.

Liangliang Zhang, Duanwei Liang, Yuan Wang, Dong Li, Jinhao Zhang, Li Wu, Mengke Feng, Fan Yi, Luzheng Xu, Liandi Lei, Quan Du and XinJing Tang*

8.668

16

Rh-catalyzed aerobic oxidative cyclization of anilines, alkynes, and CO

Chem. Sci.

Xinyao Li, Jun Pan,  Hao Wu, Ning Jiao

8.668

17

The use of electronic-neutral penetrating peptides cyclosporin A to deliver pro-apoptotic peptide: A possibly better choice than positively charged TAT

Journal of Controlled Release

Wei Gao, Xiucong Yang, Zhiqiang Lin, Bing He, Dong Mei, Dan Wang, Haoran Zhang, Hua Zhang, Wenbing Dai, Xueqing Wang, Qiang Zhang

8.450

18

Treating metastatic triple negative breast cancer with CD44 neuropilin dual molecular targets of multifunctional nanoparticles. Biomaterials 137 (2017) 23-36.

Biomaterials

De-Sheng Liang, Wen-Jie Zhang, Ai-Ting Wang, Hai-Tao Su, Hai-Jun Zhong, Xian-Rong Qi*.

8.402

19

Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone.

J Control Release

Wu L, Chen J, Wu Y, Zhang B, Cai X, Zhang Z, Wang Y, Si L, Xu H, Zheng Y, Zhang C, Liang C, Li J,Zhang L, Zhang Q, Zhou D

7.786

20

Taming the Wildness of "Trojan-Horse" Peptides by Charge-Guided Masking and Protease-Triggered Demasking for the Controlled Delivery of Antitumor Agents.

ACS Applied Materials & Interfaces

Shi, Nian-Qiu; Qi, Xian-Rong*.

7.504

21

Mechanisms of pH-sensitivity and cellular internalization of PEOz-b-PLA micelles with varied hydrophilic/hydrophobic ratios and intracellular trafficking routes and fate of the copolymer

ACS Applied Materials and Interfaces

Dishi Wang, Yanxia Zhou, Xinru Li, Xiaoyou Qu, Yunqiang Deng, Ziqi Wang, Chuyu He, Yang Zou, Yiguang Jin, Yan Liu*

7.504

22

Transmembrane Pathways and Mechanisms of Rod-like Paclitaxel Nanocrystals through MDCK Polarized Monolayer

ACS Appl. Mater. Interfaces

Feiyang Deng, Hua Zhang, Xing Wang, Yuan Zhang, Hongxiang Hu, Siyang Song, Wenbing Dai, Bing He, Ying Zheng, Xueqing Wang*, and Qiang Zhang

7.504

23

Azidofluoroalkylation of Alkenes with Simple Fluoroalkyl Iodides Enabled by Photoredox Catalysis

Org. Lett.

Xiaoyu Geng, Fengguirong Lin, Xiaoyang Wang, Ning Jiao

6.579

24

General Approach to Five-Membered Nitrogen Heteroaryl C-Glycosides Using a Palladium/Copper Cocatalyzed C-H Functionalization Strategy

Org. Lett.

Shuo Zhang,Youhong Niu,Xinshan Ye

6.579

25

Total Syntheses of Naucleamides A-C and E, Geissoschizine, Geissoschizol, (E)-Isositsirikine, and 16-epi-(E)-Isositsirikine

Org. Lett.

Lei Li, Paruke Aibibula, Qianlan Jia, Yanxing Jia

6.579

26

Total Syntheses of Festuclavine, Pyroclavine, Costaclavine, epi-Costaclavine, Pibocin A, 9-Deacetoxyfumigaclavine C, Fumigaclavine G, and Dihydrosetoclavine

Org. Lett.

Haichao Liu, Xiwu Zhang, Dong Shan, Mallesham Pitchakuntla, Yongfan Ma, Yanxing Jia

6.579

27

Regioselective Direct C-4 Functionalization of Indole: Total Syntheses of (–)-Agroclavine and (–)-Elymoclavine

Org. Lett.

Jianbo Lv, Bin Wang, Kuo Yuan, Yuan Wang, Yanxing Jia

6.579

28

Validation, identification and biological consequences of the site-specific O-GlcNAcylation dynamics of ChREBP

Molecular&Cellular Proteomics

Anqi Yang,Daoyuan Li,Lianli Chi,Xinshan Ye*

6.5399

29

Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix.

Drug Deliv.

Guo Y, Zhong T, Duan XC, Zhang S, Yao X, Yin YF, Huang D, Ren W, Zhang Q, Zhang X*

6.402

30

Delivery pathway regulation of 3',3'-bis-peptide-siRNA conjugate by nano-carrier architecture engineering

Molecular Therapy-Nucleic Acids

J Sun, C Qiu, YP Diao, W Wei, HW Jin, Y Zheng, JC Wang*, LH Zhang, ZJ Yang*

6.392

31

Bioactivity of D-/L-isonucleoside- and 2￠-deoxyinosine-incorporated aptamer AS1411s and their regulation on DNA replication and miRNA expression

Molecular Therapy-Nucleic Acids

XM Fan, LD Sun, KF Li, XT Yang, BB Cai, YF Zhang, YJ Zhu, Y Ma, Z Guan, Y Wu, LH Zhang, ZJ Yang*

6.392

32

Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity

Redox Biology

Xiaoqing Zheng, Weiwei Ma, Ruoxuan Sun, Hanwei Yin, Fei Lin, Yuxi Liu,  Wei Xue,Huihui Zeng

6.337

33

Biosynthesis-based quantitative analysis of 151 secondary metabolites of licorice to differentiate medicinal Glycyrrhiza species and their hybrids

Anal. Chem.

Wei Song#, Xue Qiao#, Kuan Chen, Ying Wang, Shuai Ji, Jin Feng, Kai Li, Yan Lin, Min Ye*

6.32

34

Nonimmobilized Biomaterial Capillary Electrophoresis for Screening Drugs Targeting Human Glucose Transporter 1

Analytical Chemistry

Ruijun Wu, Kai Zhu, Xiaodan Zhang, Sufang Zhang, Yanmeng Liu, Jinyu Ren, Cong Li, Min Ye, and Xiaomei Ling*

6.32

35

Concurrently suppressing multidrug resistance and metastasis of breast cancer by co-delivery of paclitaxel and honokiol with polymeric micelles

Acta Biomaterialia

Ziqi Wang, Xinru Li, Dishi Wang, Xiaoyou Qu, Chuyu He, Yang Zou, Yunqiang Deng, Yao Jin, Yuanhang Zhou, Yanxia Zhou, and Yan Liu*

6.319

36

Transition State-Based Sialyltransferase Inhibitors: Mimicking Oxocarbenium Ion by Simple Amide

Journal of Medicinal Chemistry

Jian Guo, Wenming Li, Weiwei Xue, Xinshan Ye*

6.259